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Archive for the Psychoneuroimmunology Category
Mental Illness Will Hit 1 Out of 2 Adults in U.S. - Anxiety Not Well Tracked
10. September 2011 by John Schinnerer.
I have spent nearly a lifetime trying to understand, manage and fix the human mind. The mind fascinates, torments, inspires, belittles, loves, and elevates. So it was with great interest that I read that the CDC came out with a new report on mental illness, including anxiety and depression.

The Center for Disease Control just released their report, Mental Illness Surveillance Among Adults in the United States (September 2, 2011), outlining the tremendous reach that mental illness has into my life, your life and every other life in the United States of America.
Some highlights from the report…
In the United States, the economic impact of mental illness is enormous, roughly $300 billion in 2002. No more recent numbers are available, but the cost is rising.
Approximately 25% of adults in the U.S. have a mental illness. That means one out of every four individuals are dealing with some form of mental illness (e.g., anxiety, depression, other mood disorders, psychosis, OCD, ADHD, personality disorders, etc.). The report defines mental illness as all diagnosable mental disorders. Effects of mental illness may involve chronic abnormal thoughts, moods, or behaviors associated with distress and impaired functioning. The effects of mental illnesses include disruptions of daily function; incapacitating personal, social, and occupational impairment; and premature death. The most common ones are anxiety and mood disorders (e.g., depression and bipolar disorder).
Almost 50% of American adults will experience at least one mental illness in their lifetime.
Mental illness leads to more disability than any other group of illnesses. More than even heart disease and cancer!

The Mental Impacts the Physical and Vice-versa
Most mental illnesses are fundamentally intertwined with chronic medical disorders like heart disease, addiction and obesity. So the manner in which our mind works dramatically impacts how well your body works.
Mental illness is a massive public health problem. Check out these facts from the World Health Organization…
- ‘mental illness is associated with increased occurrence of chronic diseases such as cardiovascular disease, diabetes, obesity, asthma, epilepsy, and cancer;
- mental illness is associated with lower use of medical care, reduced adherence to treatment therapies for chronic diseases, and higher risks of poor health outcomes;
- mental illness is associated with use of cigarettes, chewing tobacco and abuse of alcohol;
- rates for both intentional (e.g., homicide, suicide) and unintentional (e.g., motor vehicle) injuries are 2 to 6 times higher among people with a mental illness than in the population overall;
- many mental illnesses can be managed successfully, and increasing access to and use of mental health treatment services could substantially reduce the associated death rate and
- many chronic illnesses are associated with mental illnesses, and it’s been shown that treatment of mental illnesses associated with chronic diseases can reduce the effects of both and support better outcomes.’
Interestingly, there are currently no efforts at the national or state level to track anxiety disorders. Yet, anxiety disorders occur just as frequently as depression.
What’s more, anxiety disorders are similar to depression in that they
- negatively impact daily functioning as much as depression,
- are closely tied to the stress response system in the body,
- have similar negative effects on physical health, and
- are frequently found to exist together with the same physical illnesses as those that exist in folks who suffer from depression.
In conclusion, it appears that we are lagging in monitoring the prevalence of anxiety and providing assistance for those who struggle with anxiety. Mental illness is just beginning to get adequate exposure so that we can continue to develop cutting-edge tools and technologies to help those who suffer from it. We can no longer afford to bury our heads in the sand and ignore the compounding costs of mental illness. It is time to bring mental illness into the light where it can be appropriately identified and treated without shame.
What are your thoughts on this CDC report?
How have you been affected by mental illness in your life?
Please leave a comment below to get the conversation started!
All the best,
John Schinnerer, Ph.D.
Founder, Guide to Self, Inc.
Award-winning author of Guide to Self: The Beginner’s Guide to Managing Emotion and Thought (for a free PDF version, visit http://www.GuidetoSelf.com and enter your name and email address)
Award-winning blogger on The Shrunken Mind - a top 3 blog on positive psychology
Free online anger management classes which incorporate humor and positive psychology at WebAngerManagement.com
Posted in Psychoneuroimmunology, Men's feelings, Anger management therapy, De-escalating anger, San Francisco Bay Area, Danville CA, San Ramon CA, Guilt, Free self-help book, Free online anger management course, Shame, Men's anger, Alcohol abuse, Eating disorders, Anger in the workplace, Emotion and physical health, National speakers, ADHD, Anxiety, Social anxiety disorder, Social phobia, Guide to Self, Dr. John Schinnerer, Managing stress, Measuring emotions, Depression, Emotional management, Men's emotions, The human brain, Alexithymia, Managing Sadness, Managing Anxiety, Anger Management, Counseling | Print | No Comments »
Want to Reduce Your Social Anxiety? Increase Your Salt Intake!
21. May 2011 by John Schinnerer.
For those of you who have seen me speak, teach, or who know me personally, you are well aware that social anxiety is a genetic predisposition that I have learned to manage in my own life. I have learned and teach clients scientifically-proven tools to manage anger and anxiety, such as mindfulness, self-compassion, forgiveness, if-then thinking statements, and more.
Social anxiety is a topic that is very near and dear to my heart because I have suffered the emotional distress that comes with it.
So I was quite excited to see this study which came out today that shows that higher levels of salt in the diet, while having other negative effects on the body, actually has a positive impact on those of us with social anxiety.
This study demonstrated that higher levels of sodium are associated with increased production of oxytocin (which leads to increased trust, rapport, caring, and connection) and decreased levels of pro-stress hormone angiotensin II. So higher levels of sodium actually decrease the painful feelings of social anxiety!
From an evolutionary perspective this makes tremendous sense. Imagine you are on the plains of Africa, millions of years ago, and you and your tribe are suffering from thirst and dehydration (and sodium levels are rising in the body). In this scenario, an increased level of cooperation and trust is necessary so that everyone in the tribe can get to water and share the water so everyone’s chances of survival increase.

Dying of thirst for social connection? Must have oxytocin…
——————————–
Higher Levels of Sodium Reduce Your Response to Stress, Study Shows
ScienceDaily (Apr. 5, 2011) — All those salty snacks available at the local tavern might be doing more than increasing your thirst: They could also play a role in suppressing social anxiety.
New research from the University of Cincinnati (UC) shows that elevated levels of sodium blunt the body’s natural responses to stress by inhibiting stress hormones that would otherwise be activated in stressful situations. These hormones are located along the hypothalamic-pituitary-adrenal (HPA) axis, which controls reactions to stress.
The research is reported in the April 6, 2011, issue of The Journal of Neuroscience, the official journal of the Society for Neuroscience.
“We’re calling this the Watering Hole Effect,” says Eric Krause, PhD, a research assistant professor in the basic science division of UC’s department of psychiatry and behavioral neuroscience and first author of the study. “When you’re thirsty, you have to overcome some amount of fear and anxiety to approach a communal water source. And you want to facilitate those interactions — that way everyone can get to the water source.”
Krause and his team dehydrated laboratory rats by giving them sodium chloride, then exposed them to stress. Compared with a control group, the rats that received the sodium chloride secreted fewer stress hormones and also displayed a reduced cardiovascular response to stress.
“Their blood pressure and heart rate did not go up as much in response to stress as the control group’s, and they returned to resting levels more quickly,” says Krause.
“Also, in a social interaction paradigm with two rats interacting, we found them to be more interactive and less socially anxious.”
Further research, through examination of brain and blood samples from the rats, showed that the same hormones that act on kidneys to compensate for dehydration also act on the brain to regulate responsiveness to stressors and social anxiety.
The elevated sodium level, known as hypernatremia, limited stress responses by suppressing the release of the pro-stress hormone angiotensin II. Conversely, it increased the activity of oxytocin, an anti-stress hormone.
Further research, Krause says, will examine these hormones and neurocircuits to investigate their role in social anxiety disorders and autism, a neurological disorder whose characteristics include social impairment.
“Oxytocin deficiency has been implicated in autism in previous studies,” says Krause. “We’d like to investigate the possibility that dysregulation in fluid balance during pregnancy could result in autistic disorders.”
——————————-
If you would like a FREE PDF copy of John’s award-winning book on managing anxiety and creating more positive emotions in your life, simply visit www.GuideToSelf.com, click on the yellow book icon in the top left corner of the page, then enter your name and email address on the following page. You will be immediately sent an email and given instant access to your copy of Guide to Self: The Beginner’s Guide to Managing Emotion and Thought. This award-winning self-help book is filled with the latest in scientifically proven tools and tips to help you manage anxiety, depression and anger. It also is loaded with tips and techniques to teach you cutting-edge ways to insert more positive emotions and thoughts in your life.
To life, love and laughter!
John Schinnerer, Ph.D.
Award-winning author and blogger
Founder Guide to Self, Inc.
Anger Management Coach
San Francisco Bay Area
Danville, CA
Story Source:
The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Cincinnati Academic Health Center, via ScienceDaily and EurekAlert!, a service of AAAS.
________________________________________
Journal Reference:
1. E. G. Krause, A. D. de Kloet, J. N. Flak, M. D. Smeltzer, M. B. Solomon, N. K. Evanson, S. C. Woods, R. R. Sakai, J. P. Herman. Hydration State Controls Stress Responsiveness and Social Behavior. Journal of Neuroscience, 2011; 31 (14): 5470 DOI: 10.1523/JNEUROSCI.6078-10.2011
Posted in Psychoneuroimmunology, Free self-help book, San Francisco Bay Area, Alamo CA, Optimal Human Functioning, Oxytocin, Emotion and physical health, Anger management coach, Human connection, Free online anger management course, Stress management, San Ramon CA, Emotion & productivity, Social phobia, Tips to help anxiety, Social anxiety disorder, Staying calm, Dr. John Schinnerer, Guide To Self Beginners Guide To Managing Emotion, Emotional management, Danville CA, National speakers, Men's emotions, Managing Anxiety, Positive Psychology | Print | No Comments »
Long-Term Users of Ecstasy and Thizz Risk Hardcore Brain Damage - New Study
18. April 2011 by John Schinnerer.
I have a number of angry, male, teenage clients who use ecstasy, or thizz (which is a combination of ecstasy and PHP/cocaine/meth). I’m always on the lookout for new studies that highlight the physical, cognitive and emotional effects drugs have on people. Yesterday, I found out about a brand new study from www.ScienceDaily.com.
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Ecstasy (Thizz, MDMA) Seems Prevalent in Danville, CA
‘ScienceDaily (Apr. 15, 2011) — Long term users of the popular recreational drug ecstasy (MDMA) risk structural brain damage, suggests preliminary research published online in the Journal of Neurology, Neurosurgery and Psychiatry.
Other research has suggested that people who use ecstasy develop significant memory problems, so the Dutch researchers wanted to find out if there was any clinical evidence of structural changes in the brain to back this up.
They focused on the hippocampus, which is the area of the brain responsible for long term memory.
They measured the volume of the hippocampus using MRI scans in 10 young men in their mid 20s who were long term users of ecstasy and seven of their healthy peers in their early 20s with no history of ecstasy use.
Although the ecstasy group had used more amphetamine and cocaine than their peers, both sets of young men had used similar amounts of recreational drugs, bar ecstasy, and drank alcohol regularly.
The ecstasy group had not been using on average for more than two months before the start of the study, but had taken an average of 281 ecstasy tablets over the preceding six and a half years.
The MRI scans showed that hippocampal volume in this group was 10.5% smaller than that of their peers, and the overall proportion of grey matter was on average 4.6% lower, after adjusting for total brain volume.

This indicates that the effects of ecstasy may not be restricted to the hippocampus alone, say the authors
“Taken together, these data provide preliminary evidence suggesting that ecstasy users may be prone to incurring hippocampal damage, following chronic use of this drug,” they write.
They add that their findings echo those of other researchers who have reported acute swelling and subsequent atrophy of hippocampal tissue in long term ecstasy users.
And they point out: “Hippocampal atrophy is a hallmark for diseases of progressive cognitive impairment in older patients, such as Alzheimer’s disease.”‘
…..
It’s my deep-seated belief based on experience and a pretty good (really, just pretty good, memory is NOT my strength!) understanding of the literature that most substance use is a means to escape the emotional mind - feelings such as ennui, embarrassment, anger, frustration, anxiety, depression, loneliness, alienation, excitement, disappointment, and heartache. One of the problems with ecstasy, or MDMA, is that it changes the way in which the brain perceives pleasure. Over time, the brain loses the ability to perceive pleasure without the addition of ecstasy. Without the ability to feel pleasure, chonic ex users lose the ability to ‘approach’ things they desire and increasingly ‘avoid discomfort.’

Lacking the ability to approach things they desire means that fulfilling activities are non-existent. So goal-setting and, more importantly, goal achievement, a major source of meaning and personal satisfaction, do not happen.
On the bright side, research has shown that the brain can recover rapidly, creating new neurons and new pathways. Changes in the brain occur every minute of every day. Your brain is always growing, developing, learning, and recreating itself!
My goal is to help you realize where you are, what you are missing (the hardest part), and to take small steps in a constructive, meaningful direction.
This is done through teaching tools such as self-forgiveness, mindfulness (sounds weak but is tremendously powerful), compassion, challenging catastrophic thinking, reframing, best possible self and more. By layering these tools one atop the other, there is a cumulative, additive effect wherby my clients become less filled with negative emotions (e.g., anger, guilt, anxiety, sadness) and more open to positive emotions (e.g., curiosity, awe, hope, courage, pride, and contentment).
All the best,
John Schinnerer, Ph.D.
Founder, Guide to Self, Inc.
If you are interested in finding out more, you can download a FREE copy of John’s award-winning book, Guide to Self: The Beginner’s Guide to Managing Emotion and Thought. It is awesome! Just visit, www.GuideToSelf.com click on the picture of the yellow book on the left side of the screen and enter your name and email address in the required fields. This will also give you access to a bunch of free anger management online video classes. What could be better in this day and age of falling economies, changing breadwinner roles, and political correctness and incorrect polititicians?!
Also, be sure to check out John’s offering on the latest proven tools for anger management at http://webangermanagement.com.
Posted in De-escalating anger, Parenting adolescents, Psychoneuroimmunology, Self-help book, Anger management therapy, San Francisco Bay Area, Alamo CA, Meaning-making, Brain plasticity, Optimal Human Functioning, Self-compassion, Managing anger, Guilt, Managing Pain, Online anger management class, Long-term memory, Ecstasty and Thizz, Free online anger management course, Compassion, Courage and Anxiety, Free self-help book, Anger in the workplace, Stress management, San Ramon CA, Emotion & productivity, Anxiety, Guide To Self Beginners Guide To Managing Emotion, Depression, Parenting, Emotional IQ, Guide to Self, Forgiveness, Managing stress, Dr. John Schinnerer, Life coach, Emotional management, Managing Anxiety, Curiosity, National speakers, Emotion & learning, Danville CA, Awareness, Hope, Anger Management, Managing Sadness, Men's emotions, The human brain, Positive Psychology | Print | No Comments »
Mindfulness Shown to Reduce Pain Perception By 40%
6. April 2011 by John Schinnerer.
From KurzweilAI.net…
Demystifying meditation — brain imaging illustrates how meditation reduces pain
April 6, 2011 by Editor
Researchers at Wake Forest Baptist Medical Center have shown that meditation produces a 40 percent reduction in pain intensity and a 57 percent reduction in pain unpleasantness.

Fifteen healthy volunteers (who had never meditated) attended four 20-minute classes to learn a meditation technique known as “focused attention.” This is a form of mindfulness meditation where people are taught to attend to the breath and let go of distracting thoughts and emotions.
Both before and after meditation training, study participants’ brain activity was examined using arterial spin labeling magnetic resonance imaging (ASL MRI) to capture longer duration brain processes. During these scans, a pain-inducing heat device was placed on each participant’s right leg. This device heated a small area of their skin to 120 degrees Fahrenheit, a temperature that most people find painful, over a 5-minute period.
Scans taken after meditation training showed that the pain ratings for every participant were reduced.
At the same time, meditation significantly reduced brain activity in the primary somatosensory cortex, an area that is crucially involved in creating the feeling of where and how intense a painful stimulus is.
The research also showed that meditation increased brain activity in areas including the anterior cingulate cortex, anterior insula and the orbito-frontal cortex, which shape how the brain builds an experience of pain from nerve signals from the body. The more these areas were activated by meditation, the more that pain was reduced.
The decreases ranged from 11 to 93 percent, which is a greater reduction in pain than with morphine or other pain-relieving drugs, says researcher Fadel Zeidan, Ph.D.
Zeidan and colleagues believe that meditation has great potential for clinical use because so little training was required to produce such dramatic pain-relieving effects. “This study shows that meditation produces real effects in the brain and can provide an effective way for people to substantially reduce their pain without medications,” he said.
Their work appears April 6 in The Journal of Neuroscience.
For a FREE PDF copy of John’s award-winning self-help book on proven exercises to turn down the volume on negative emotions and ways to turn up the volume on positive emotions, including mindfulness tips, visit GuideToSelf.com. Click on the yellow book icon and enter your name and email address for instant access!
For FREE online anger management courses, visit WebAngerManagement.com where you can have full access to 4 free anger management classes by anger management expert John Schinnerer, Ph.D.
There is also a full 10 week course on Positive Psychology of Anger Management available at the same site for the ridiculously low price of $297.
Posted in Free self-help book, Managing anger, Anger management therapy, Psychoneuroimmunology, Anger in the workplace, Emotion and physical health, Online anger management class, Managing Pain, Free online anger management course, Well-being, Optimal Human Functioning, Anger Management, Emotional management, Guide To Self Beginners Guide To Managing Emotion, Dr. John Schinnerer, Men's emotions, Mindfulness, Brain plasticity, San Ramon CA, Danville CA, Positive Psychology | Print | No Comments »
Does social anxiety disorder respond to therapy? New study says yes
15. February 2011 by John Schinnerer.
February 14, 2011
When psychotherapy is helping someone get better, what does that change look like in the brain? This was the question a team of Canadian psychological scientists set out to investigate in patients suffering from social anxiety disorder. Their findings are published in Psychological Science, a journal of the Association of Psychological Science.

Social anxiety is a common disorder, marked by overwhelming fears of interacting with others and expectations of being harshly judged. Medication and psychotherapy both help people with the disorder. But research on the neurological effects of psychotherapy has lagged far behind that on medication-induced changes in the brain.
“We wanted to track the brain changes while people were going through psychotherapy,” says McMaster University Ph.D. candidate Vladimir Miskovic, the study’s lead author.
To do so, the team—led by David Moscovitch of the University of Waterloo, collaborating with McMaster’s Louis Schmidt, Diane Santesso, and Randi McCabe; and Martin Antony of Ryerson University—used electroencephalograms, or EEGs, which measure brain electrical interactions in real time. They focused on the amount of “delta-beta coupling,” which elevates with rising anxiety.
The study recruited 25 adults with social anxiety disorder from a Hamilton, Ontario clinic. The patients participated in 12 weekly sessions of group cognitive behavior therapy, a structured method that helps people identify—and challenge—the thinking patterns that perpetuate their painful and self-destructive behaviors.
Two control groups—students who tested extremely high or low for symptoms of social anxiety—underwent no psychotherapy.
The patients were given four EEGs—two before treatment, one halfway through, and one two weeks after the final session. The researchers collected EEG measures of the participants at rest, and then during a stressful exercise: a short preparation for an impromptu speech on a hot topic, such as capital punishment or same-sex marriage; participants were told the speech would be presented before two people and videotaped. In addition, comprehensive assessments were made of patients’ fear and anxiety.
When the patients’ pre- and post-therapy EEGs were compared with the control groups’, the results were revealing: Before therapy, the clinical group’s delta-beta correlations were similar to those of the high-anxiety control group and far higher than the low-anxiety group’s. Midway through, improvements in the patients’ brains paralleled clinicians’ and patients’ own reports of easing symptoms. And at the end, the patients’ tests resembled those of the low-anxiety control group.
“We can’t quite claim that psychotherapy is changing the brain,” cautions Miskovic. For one thing, some of the patients were taking medication, and that could confound the results. But the study, funded by the Ontario Mental Health Foundation, is “an important first step” in that direction—and toward understanding the biology of anxiety and developing better treatments.
The work might also alter perceptions of therapy. “Laypeople tend to think that talk therapy is not ‘real,’ while they associate medications with hard science, and physiologic change,” says Miskovic. “But at the end of the day, the effectiveness of any program must be mediated by the brain and the nervous system. If the brain does not change, there won’t be a change in behavior or emotion.”
Provided by Association for Psychological Science
From www.PhysOrg.com
Have a fantastic Valentine’s Day!
Cheers,
John Schinnerer, Ph.D.
Founder Guide to Self, Inc.
Positive psychology of anger management
Turning down the volume on anger
For your complimentary copy of John’s award-winning self-help book, Guide to Self: The Beginner’s Guide to Managing Emotion and Thought, visit www.GuideToSelf.com and enter your name and email address for instant access to a PDF version! It’s 216 pages of life-altering tools to make the most of your mind.
Posted in San Francisco Bay Area, Well-being, Optimal Human Functioning, Brain plasticity, Emotion & productivity, San Ramon CA, Psychoneuroimmunology, Self-help book, Emotion and physical health, Stress management, Free self-help book, Courage and Anxiety, Self-improvement book, Emotion and technology, Resiliency, Anxiety, Staying calm, Emotional IQ, Dr. John Schinnerer, Measuring emotions, Social anxiety disorder, Tips to help anxiety, Managing Anxiety, Men's emotions, Emotional management, Guide To Self Beginners Guide To Managing Emotion, Happiness, Positive Psychology | Print | No Comments »